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... he tumor samples with spontaneous regression potential, Tang Shun’s team indeed discovered some interesting patterns: their TIM expression tended to be less stable, showing heterogeneity between different regions of the same tumor and even between different cells. Certain TIM subtypes exhibited a subtle reciprocal relationship in expression with a set of genes known as "cell fate checkpoints," including some apoptotic factor primers. Single-cell data revealed that cancer cells with the lowest or ...

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