MTL - I Became A Virtuous Wife and Loving Mother in another Cultivation World - Chapter 211 I am really evil.

Amamiya Hiroto is unlucky. His life consisted of misfortune after misfortune, culminating in an unlucky death during an incident on a school boat trip, trying to save a girl he barely knew. After death, he met a god of reincarnation who requested that the hundred or so dead passengers—one of them being the girl he tried in vain to save—be reincarnated into another world.

Vahn was an atypical youth. Due to a rare mutation, his blood had the potential to target and attack ailments within the human body. Touted as a universal cure, people had elevated his status above the norm and given him the classification "Panacea". In the media, he was hailed as a great hero who would usher in a new era or human wellness. However, behind the scenes things weren't so bright. Being a unique individual, Vahn spent his entire youth locked up in a lab with various scientists and research teams using his body and blood to perform endless amounts of experiments. The only solace in his suffering was the various anime and manga made available to him between experiments. He often imagined himself as the protagonist in a world of his own, finally in control of his own destiny. For years he nurtured this desire, until at the age of 14 he died when an organization had tried to kidnap him from the lab...

She was originally an assassin. After rebirth, she was reduced to another world’s Di family’s most inferior concubine-born daughter. With an extremely hideous appearance and no way to cultivate, she was the object of everyone’s humiliation and bullying.