I Woke the Sick and Disabled Prince on Our Wedding Night - Chapter 41 - She’s My Wife. I’ll Accompany Her

One day, Luo Jian woke up from his sleep and found himself in a locked chamber where the door and window were all sealed. A note with a few lines written on it was tacked to the wall: “Escape from this room within an hour, otherwise, you will die.”

There is a sequel called Reincarnation Night (轮回之夜) that takes place in the same universe but has different main characters

- Description from Novelupdates

Cultivation destroyed, eyes poisoned blind and robbed of her status in the household?Luo Qingtong narrows her eyes and sneers, “Bring it on! Let me teach you a lesson!”A 24th Century Supreme Vision Master transmigrates to become the incapacitated genius daughter of the Marquis Household in a lower-class country.With a pair of powerful blood-red eyes armed with the ability to appraise treasures, see through things, heal, poison and break through defenses... She is invincible!A spirit and martial arts cultivator, an expert in weapons and medicine, a master in controlling beasts and deploying formations...She is the embodiment of the ultimate supremacy and unrivaled arrogance!Never does she expect to get involved with a person who is even more wicked than her. From then on, it becomes a game of I-run-you-catch. When you kill someone, I’ll hand you the knife.Together, let’s wreak havoc in the world!

Alex is a young man who struggles to make a living in the world's biggest game (Ancient world). He works as a mercenary who does every job he can find. It's been five years since his suffering started.

Ancient World creation was only possible by the World's greatest invention, “AI ZERO.”

Ancient World A vast planet Multiple times the size of Earth Ruled by Great empires, Big organizations, and hidden Shadowy associations.

A Fantasy world filled with prehistoric animals that have gone extinct on Earth. The creatures humans have only heard of in fairy tales and old stories, Monsters beyond the imagination of humans, roam the vast lands of the “Ancient World.”

Everything was going well, but it all changed on that day.

When the United States told the World “AI ZERO.” and “Ancient World.” technology was a gift from a very advanced intergalactic civilization. That has surpassed humanity in any way of life by an uncountable margin.

Humanity entered a new era, and the Ancient World became humankind's most important part of life.

Alex joined the game to make a living and support his family, but things didn't go as he had hoped.

After suffering in the Ancient world, Alex returned five years back in time.

Alex knows that the Ancient World is not just a VR game.

Now with a new chance in life, Alex will get strong and reach the top while finding the truth about the Ancient World.

After his parents died, Alex Roth had a plan: become a wizard. Through hard work, he was accepted into the world’s greatest university of wizardry—but fate had another plan.

On his eighteenth, he is marked as one of his kingdom’s five Heroes, chosen to fight the land’s great enemy. But his brand is 'The Fool', worst of the marks.

Rather than die or serve the other Heroes like Fools in the past, he packs up his little sister, his childhood friend and her cerberus, then flees for the university in hope of refuge, magic and to unravel the truth about his land’s evil.

There’s one small problem: The Mark tries to ruin magic while enhancing skills outside of divinity, combat and spellcraft.…

…that is, unless he can learn to exploit the hell out of it.